Table 1. Correlation of hATT-CMs score with tumor stage and histological grade.

hATT-CM	Score	Stage	HG
“25”	-2.69	IIb	HG3
“20”	-1.47	IIa	HG3
“22”	-1.31	I	HG2
“30”	-1.17	I	HG2
“19”	-1.17	I	HG2
“27”	-0.44	I	HG1

Score in the canonical axis of each hATT-CM from the discriminant analysis (Figure 3C) correlated with tumor stage and histological grade (HG). Nonparametric Spearman correlation test was performed between score and tumor stage and between score and HG. In both cases, correlation was significant (p<0.05). A more negative score represents a hATT sample more different from the hATN group. Thus, the sample with a score closer to 0 (“27”) is the most similar within the hATT-CM to a hATN-CM and this goes in line with the lower tumor stage and HG of the tumor from that patient.