Author response table 4. Ratio of expression values, with minimum expression threshold of RPKM>1 and maximum expression threshold of RPKM<5.

We normalized by the ancestral state of expression. Level of significance (Wilcoxon test *P-value<0.05, **P-value<0.001, ***P-value<0.0001, N.S. P-value>0.05.

	S. japonicum schistosomula	S. japonicum adults	S. mansoni schistosomula	S. mansoni adults
Female Z:A	0.82*	0.79 N.S.	0.90 N.S.	1.05 N.S.
Male Z:A	1.22 N.S.	1.17 N.S.	1.22 N.S.	1.50*
Z(F:M) / A(F:M)	0.67***	0.67*	0.74*	0.70*
Z(fem): Z(male)	0.62*	0.66 N.S.	0.79 N.S.	0.72 N.S.
A(fem): A(male)	0.93 N.S.	0.98 N.S.	1.07 N.S.	1.02 N.S.
N (Z)	11	8	23	16
N (A)	486	321	486	321