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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Curr Opin Genet Dev. 2018 Mar 9;50:86–95. doi: 10.1016/j.gde.2018.02.009

Figure 3.

Figure 3

Effect size (in kg, assuming a 1.7m tall person) by MAF for GWAS-identified BMI loci (Panel A) and their cumulative explained variance (Panel B). Color coding corresponds with year of discovery and dotted line represent trends of effect sizes by year. Effect size (in kg, assuming a 1.7m tall person) by MAF for low-frequency and rare exomechip-identified loci (Panel C) [Adapted from Turcot et al. [42]]. Filled markers indicate that the minor allele is associated with higher BMI, and unfilled markers indicate that the minor allele is associated with lower BMI. The dotted line represents 80% power.