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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Clin Immunol. 2018 Jun 19;194:9–18. doi: 10.1016/j.clim.2018.06.005

Figure 5: STAT6 and PPARG expression changes similarly in responders and nonresponders.

Figure 5:

Total RNA was extracted from peripheral blood CD14+ monocytes; gene expression was determined using RT-PCR, as described in Material and Methods. X-Axis indicates the number of weeks (W) of treatment with rilonacept. Early (responders): achieved ACR Pedi 30 before 4 weeks or less of treatment; Late (responders): more than 4 weeks of treatment to achieve ACR Pedi 30. Boxplots extend from the 25th to 75th percentiles, and the whiskers extend from the minimum to the maximum point; middle lane represents the median. Y-axis shows log10 scale. Statistical analysis used mixed effects regression model. All comparisons p>0.05, and deemed non-significant.