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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Am J Surg Pathol. 2018 Sep;42(9):1166–1181. doi: 10.1097/PAS.0000000000001111

Figure 8.

Figure 8

So-called “oncocytoid RCC after neuroblastoma” now shown to harbor TSC mutations. This neoplasm occurred in a 40-year-old female with a distant history of neuroblastoma treated with surgery and radiation. The neoplasm was encapsulated in most areas but directly abutted the native renal parenchyma in other areas (A). The neoplasm had solid to papillary architecture (B) with some areas demonstrating prominent foam cells (C). The neoplastic cells had voluminous cytoplasm and demonstrated characteristic granular cytoplasmic stippling typically seen in ESC (D). The neoplasm demonstrated two TSC2 mutations.