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. 2018 Jun 28;42(3):1537–1547. doi: 10.3892/ijmm.2018.3748

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Copyright: © Yan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Downregulation of miRNA-145 suppresses p-Akt3 and p-mTOR protein expression in an in vitr model of acute myocardial infarction. (A) Bioinformatics software analysis identified the targeted association between miRNA-145 and Akt3. (B) Representative image and quantification of (C) p-Akt3 and (D) p-mTOR protein expression levels detected via western blotting. ^##P<0.01 vs. control group. miRNA, microRNA; control, control group; anti-miRNA-145, miRNA-145 downregulated group; p, phosphorylated; Akt3, RAC-γ serine/threonine-protein kinase; mTOR, mechanistic target of rapamycin.