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Hypoxia induces the expression of CXCR4 in JEG3 cells. (A) mRNA expression of CXCR4 was detected by reverse transcription-quantitative polymerase chain reaction analysis in JEG3 cells exposed to 3% O2 for the indicated periods of time (**P<0.05). (B) Protein levels of HIF-1α and CXCR4 were analyzed by western blotting. β-actin was used as an internal control. CXCR4, CXC chemokine receptor 4; HIF-1α, hypoxia-inducible factor 1α.
