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. 2018 Jun 7;42(3):1283–1294. doi: 10.3892/ijmm.2018.3721

Figure 4.

Figure 4

Silencing of hTERT expression impaired oral squamous cell carcinoma cell viability, proliferation and cell cycle arrest. (A) Cell viability was determined by MTT assay following silencing of hTERT in SCC-25 and UM1 cells. (B) Cell proliferation ability was measured by MTT assay following silencing of hTERT in SCC25 and UM1 cells. (C) Cell cycle distribution was analyzed following silencing of hTERT in SCC-25 and UM1 cells. Data are presented as the mean ± standard deviation. Each assay was performed independently at least three times. #P<0.05 vs. NC. hTERT, human telomerase reverse transcriptase; NC, negative control; sh, short hairpin RNA; OD, optical density.