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. 2018 Jun 21;42(3):1411–1417. doi: 10.3892/ijmm.2018.3738

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Kushui Rose decoction (KRD) significantly inhibits the multivulva (Muv) phenotype of the let-60(gf) mutants in a dose-dependent manner. The Muv phenotype of let-60(gf) mutants was reversed to the wild-type phenotype after treated with KRD for 3–4 days. The proportion of wild-type of let-60(gf) was the percents of wild phenotype worms in tested worms (N=80–100). C, control. RDL, RDM, RDH refer to 0.1, 0.2 and 0.4 mg/ml KRD, respectively. Data are presented as the mean ± SD of at least three independent experiments. Bars with different letters indicate that there was a significant difference at a level of 0.05 among groups.