Table 1.
Experimental design.
| Group | Number of birds | Treatment | Treatment day | Challenge dose and day | Sampling day |
|---|---|---|---|---|---|
| 1- (UC) | 8 | — | — | — | 37 days of age |
| 2- (CC) | 8 | PBS | 14 days of age | 107 CFUs of C. jejuni 15 days of age |
37 days of age (22 days post-challenge) |
| 3- (ECpGL) | 8 | 5 µg ECpG ODN | 14 days of age | 107 CFUs of C. jejuni 15 days of age |
37 days of age (22 days post-challenge) |
| 4- (ECpGH) | 8 | 25 µg ECpG ODN | 14 days of age | 107 CFUs of C. jejuni 15 days of age |
37 days of age (22days post-challenge) |
| 5- (LL) | 8 | Low dose ofC. jejuni lysate | 14 days of age | 107 CFUs of C. jejuni 15 days of age |
37 days of age (22 days post-challenge) |
| 6- (LH) | 8 | High dose of C. jejuni lysate | 14 days of age | 107 CFUs of C. jejuni 15 days of age |
37 days of age (22 days post-challenge) |
UC = unchallenged, untreated control; CC = C. jejuni-challenged; ECpGL = a low dose (5 µg) of encapsulated CpG ODN; ECpGH = a high dose (25 µg) of ECpG ODN; LL = a low dose (4.3 µg protein) of C. jejuni lysate (LL); LH = a high dose (21.5 µg protein) of C. jejuni lysate (LH).