Table 2.
Correlations between the proportion of CD11c+HLA-DR+ and CD80+CD83+ DCs and DCs endocytotic activity and the phenotype of cancer cells which were the source of lysates or TCM for given analysis (*p < 0.05, Spearman’s rank correlation coefficient).
| DC CD11c+HLA-DR+ | DC CD80+CD83+ | |||||||
|---|---|---|---|---|---|---|---|---|
| LYSATE | TCM | LYSATE /LPS | TCM /LPS | LYSATE | TCM | LYSATE /LPS | TCM /LPS | |
| CD133+ | −0.44 | −0.08 | −0.15 | −0.15 | −0.72* | −0.62* | −0.76* | −0.77* |
| CD133+CD44+CD29+ | 0.18 | 0.25 | 0.22 | 0.24 | −0.28 | −0.15 | −0.60* | −0.59* |
| CD133-CD44+CD29+ | 0.41 | 0.22 | 0.54 | 0.50 | 0.22 | 0.40* | 0.00 | 0.00 |
| CD133-CD44+CD29- | −0.62* | −0.63* | −0.98* | −0.97* | −0.46 | 0.03 | 0.39 | 0.41 |
| CD133-CD44-CD29+ | −0.12 | −0.06 | −0.38 | −0.38 | −0.48* | −0.37* | −0.38* | −0.39* |
Lysates and TCM (tumor conditioned medium) used in these analyses were collected from cultures of HCT116 and HT29 CRC lines expanded in spherical form (allogenic) and CRC patients CSCs in the form of spheroids (autologous).