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. 2018 Aug 13;8:12031. doi: 10.1038/s41598-018-30229-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Phylogenic analysis of the full HBV genomes. (A) Phylogenic tree construction displaying clustering of various genotype F strains. Red dots correspond to HBV isolates assembled for the present study; all of them were clustered within the sub-genotype F1b. (B) Shannon entropy diagram of the 12 HBV isolates from Peruvian patients below (n = 6) (upper panel) and above age 37 (n = 6) (lower panel). Presence of blue lines indicates nucleotide diversity at corresponding position.