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. 2018 Aug 13;8:12031. doi: 10.1038/s41598-018-30229-8

Figure 5.

Figure 5

Cellular gene expression analysis. (a) Gene-expression correlation matrix of the 121 genes on 40 HCC/NTL matched pairs. Black and white squares above the matrix indicate tumor and non-tumor liver tissues, respectively. (b) Box-and-whiskers plots on coefficients of variation of the gene expressions of the 121 genes in the 40 HCC (CV T) and 40 NTL (CV N). P value is given by a Mann-Whitney U test. (c) Bar chart of differential expression between the 40 HCC and the 40 corresponding NTL in the viral restriction and DNA repair groups of genes. For each gene, a paired t test or Wilcoxon matched-pairs signed rank test were used as appropriate. (d) Volcano plot representing mean fold changes and P values of expression affecting the 78 DNA repair genes between the 40 HCC and 40 corresponding NTL. −Log10 of P values were either obtained by Student t test or Mann-Whitney U test depending on the distribution of values as assessed by a F-test.