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. 2018 Aug 7;9:1596. doi: 10.3389/fimmu.2018.01596

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Copyright © 2018 Abudukelimu, Barberis, Redegeld, Sahin and Westerhoff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The levels of three network components involved in inflammation, i.e., healthy fibroblasts (A), TNF-α (B), and antigen (CRA) (C) as functions of time after increasing (at time 0) the CRA influx level. Full line: no increase in CRA influx, i.e., maintained at 5.0 fM/min. Yellow dashed line: CRA influx increased from 5 to 20 fM/min. The blue dotted line: CRA influx increased from 5 to 30 fM/min.