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SAMC slightly increased the apoptosis of normal hepatocyte cell line LO-2. (A)–(C) Change of apoptotic ratio and activity of caspase-3, 7, 8 after two doses of SAMC incubation for 24 h. (D) Representative Western blot images for the protein changes of key apoptotic markers, cleaved PARP, BCL-2, and FADD in Huh-7 cells. Data are presented in means±SEM. *P<0.05, **P<0.01 and ***P<0.001, respectively between indicated groups.
