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. 2018 Aug 7;9:1678. doi: 10.3389/fmicb.2018.01678

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Copyright © 2018 Chen, Sun, Yang, Song and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo assays. (A) Distribution of phage PHB02 in mice. The experiment was repeated three times and results are expressed as the mean ± SD. (B) Scores of clinical symptoms post-challenge. The health status of each group of mice was given a score between zero and five, as follows: five: normal health, condition unremarkable; four: decreased physical activity and ruffled fur; three: lethargy and hunched back; two: exudative accumulation around partially closed eyes; one: near death; zero: dead. The total score for each group was recorded at least three times per day. The data are expressed as the mean ± SD.