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Response to individual boluses in the two groups.
| HTS (n = 30) | Mannitol (n = 30) | P-value | |
|---|---|---|---|
| Initial elevated ICP (mmHg) | 28.43 ± 6.92 | 30.27 ± 6.12 | 0.282 |
| ICP reduction (mmHg) | 7.50 ± 2.45 | 6.13 ± 1.79 | 0.017 |
| Efficacy of individual doses | 0.009 | ||
| Effective doses (n) | 18 | 8 | |
| Ineffective doses (n) | 12 | 22 |
HTS, hypertonic saline; ICP, intracranial pressure.
