Table 2.
Percentages of explained variation (PEV) of factors of/ and the final LASSO Cox regression model.
| Clinic/Genes | PEV | Partial PEV | Total PEV |
|---|---|---|---|
| Age | 12.80% | ||
| FIGO stage | |||
| Residual tumor | |||
| SLCO4C1 (categorical and continuous) | 0.99% | ||
| SLCO5A1 (categorical and continuous) | 5.08% | ||
| SLCO1B7 | 0.32% | ||
| SLCO2A1 | 1.12% | ||
| ABCC2 | 0.84% | ||
| ESR1 | 1.08% | ||
| ABCB2/ABCB3/ABCC4/HER2 | 0.08% | ||
| 23.13% |
The corresponding PEVs for the final multi-variable Cox model are shown (starting from 12.80% for the model including only the three clinicopathological factors). After including all seven additional predictors, a PEV of 23.13% was reached. The categorical and continuous variables for SLCO4C1 and SLCO5A1 were used together (see Figure 2).