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. 2018 Jun 20;16(2):1470–1476. doi: 10.3892/etm.2018.6330

Figure 1.

Figure 1.

NOB alleviated the OGD/R injury in PC12 cells. (A) The cytotoxic effects of NOB (1, 10, 20, and 50 µM) on PC12 cells were evaluated using a CCK-8 assay. The four concentration of NOB displayed no cell toxicity on PC12 cells. The effects of NOB (1, 10, 20, and 50 µM) on the cell viability (B) and the LDH release (C) after OGD/R insult. Data are expressed as the mean ± standard deviation (n=3). *P<0.05, compared with the control; #P<0.05, compared with the OGD/R. NOB, nobiletin; OGD/R, oxygen-glucose deprivation and reoxygenation; LDH, lactate dehydrogenase; CCK-8, Cell Counting Kit-8.