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. 2018 Jun 15;16(2):1483–1492. doi: 10.3892/etm.2018.6319

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Figure 2. — Peripheral blood mtDNA-CN is decreased with the severity of DN. The association between mtDNA-CN and the severity of DN was analyzed in the patient groups stratified based on albumin-to-creatinine ratio into type 2 diabetes mellitus patients with normoalbuminuria (n=50), DN patients with microalbuminuria (n=29) and DN patients with macroalbumiuria (n=21). **P<0.01 compared with normoalbuminuria and ^##P<0.01 compared with microalbuminuria. mtDNA-CN, mitochondrial DNA copy number; DN, diabetic nephropathy.