Figure 1.

SIRT5 expression is significantly upregulated in patients with type 2 diabetes. (A) mRNA levels of SIRT5 in diabetic patients and healthy volunteers were detected using reverse transcription quantitative polymerase chain reaction analysis. Each experiment was repeated three times. (B) Pearson's correlation analysis was performed to determine the association between the SIRT5 expression and blood glucose levels in patients with type 2 diabetes. The results are presented as the mean ± standard deviation. *P<0.05 vs. healthy volunteers. SIRT5, sirtuin 5.