Table IV.

Results on top five GO functions and KEGG pathway enrichment analysis of differentially expressed genes.

Function and pathway	ID	Description	Count in gene set	False discovery rate
Biological process	GO: 0001501	Skeletal system development	20	2.03×10−20
(GO)	GO: 0009888	Tissue development	27	3.18×10−19
	GO: 0001503	Ossification	16	2.27×10−18
	GO: 0071495	Cellular response to endogenous stimulus	21	4.40×10−18
	GO: 0071363	Cellular response to growth factor stimulus	17	5.39×10−18
Molecular function	GO: 0046332	Mothers against decapentaplegic homolog binding	10	5.84×10−14
(GO)	GO: 0005515	Protein binding	32	4.67×10−13
	GO: 0005160	Transforming growth factor β receptor binding	8	1.02×10−11
	GO: 0005126	Cytokine receptor binding	10	1.09×10−9
	GO: 0019838	Growth factor binding	8	1.58×10−9
Cellular component	GO: 0005615	Extracellular space	20	2.99×10−13
(GO)	GO: 0044421	Extracellular region part	26	2.01×10−10
	GO: 0005576	Extracellular region	27	3.32×10−10
	GO: 0031012	Extracellular matrix	12	3.32×10−10
	GO: 0005578	Proteinaceous extracellular matrix	11	1.35×10−9
KEGG pathways	4350	Transforming growth factor-β signaling pathway	13	1.50×10−20
	5200	Pathways in cancer	17	2.04×10−19
	4390	Hippo signaling pathway	12	1.87×10−15
	5205	Proteoglycans in cancer	12	1.53×10−13
	4151	Phosphoinositide 3-kinase-protein kinase B signaling pathway	12	2.49×10−11

GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.