FIGURE 5.

Pregravid obesity is not associated with structural changes in its placental microbiome. (A) Median relative abundance of microbial communities at the phylum level reported by QIIME. No significant differences were observed. (B) Differences in the relative abundance of Bacteroides detected by both edgeR and Linear Discriminant Analysis (LDA) (p < 0.01). (C) LDA of PICRUSt-predicted KEGG functions of microbial communities in the placentas from lean and obese subjects identified using LEfSe. Significant differences between groups are indicated as follows: ^∗∗p < 0.01.