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. 2018 Jun 12;16(2):1225–1231. doi: 10.3892/etm.2018.6288

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Downregulation of miR-423-5p in colon cancer tissues. (A) RT-qPCR analysis of miR-423-5p expression in 25 pairs of normal colon and colon cancer tissue. (B) Logistic regression analysis between miR-423-5p expression in tumor tissues and tumor grade (tumor grade I, n=6; tumor grade II–III, n=11; tumor grade IV, n=8). (C) RT-qPCR analysis of miR-423-5p expression in the plasma of 25 patients and healthy controls. (D) Logistic regression analysis between plasma miR-423-5p expression and tumor grade (tumor grade I, n=6; tumor grade II–III, n=11; tumor grade IV, n=8). (E) RT-qPCR analysis of miR-423-5p expression in HCoEpiCs and colon cancer cell lines. n=3. Values are expressed as the mean ± standard deviation. **P<0.01 and ***P<0.001 vs. HCoEpiC. miR-423-5p, microRNA-423-5p; reverse transcription-quantitative polymerase chain reaction; HCoEpiCs, human colon epithelial cells.