Table 3.

Performance of RDTs for HBeAg detection (Group 1, Group 2 and East Asian samples)

	Senegalese samples*				East Asian samples
	Group 1: HBeAg-positive cases (N = 48)		Group 2: HBeAg-negative controls (N = 196)		HBeAg-positive cases (N = 17)
	Sensitivity	95% CI	Specificity	95% CI	Sensitivity	95% CI
SD Bioline	29.8% (14/47)	17.3–44.9	100% (196/196)	98.1–100	47.1% (8/17)	23.0–72.2
Insight	31.1% (14/45)	18.2–46.6	100% (196/196)	98.1–100	52.9% (9/17)	27.8–77.0
OneStep	42.5% (17/40)	27.0–59.1	98.4% (183/186)	95.4–99.7	35.3% (6/17)	14.2–61.7

HBeAg = hepatitis B e antigen; RDT = rapid diagnostic test.

^*Discordant results on each RDT between two laboratory staff were excluded (SD Bioline, N = 1; Insight, N = 3; OneStep, N = 2).