Table 1.
Infection rates of Sprague–Dawley rats following intranasal exposure to individual isolates of Leptospira licerasiae serovar Varillal as determined by quantitative polymerase chain reaction of kidney tissue
L. licerasiae strains | Isolate source | n | Infected | Percentage |
---|---|---|---|---|
MMD4787 | Proechimys sp. | 3 | 0 | 0 |
MMD3847 | Proechimys brevicauda | 3 | 1 | 33.33 |
HAI1026 | Human | 3 | 2 | 66.66 |
VAR10 | Human | 3 | 2 | 66.66 |
MMD3782 | Metachirus nudicaudatus | 3 | 0 | 0 |
MMD3795 | P. brevicauda | 3 | 2 | 66.66 |
CEH008 | Rattus norvegicus | 3 | 0 | 0 |
CEH006 | R. norvegicus | 3 | 1 | 33.33 |
MMD4847 | Uroderma magnirostrum* | 3 | 0 | 0 |
Total | – | 27 | 8 | 29.6 |
CEH indicates peridomestic rodents trapped near houses, MMD indicates wild-caught rodents trapped along a forest transect, VAR and HAI indicate strains isolated from human cases at health centers. The study during which strains were isolated was approved by the Human Subjects Protection Program, University of California San Diego, and the Ethical Committees of Asociacion Benefica PRISMA, Lima, Peru, and Universidad Peruana Cayetano Heredia, Lima, Peru. Animal trapping and use for was approved by the Instituto Nacional de Recursos Naturales of Peru (INRENA), Lima, Peru, and the Institutional Animal Care and Use Committee, University of California San Diego.