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Effect of anti-TNF-α treatment on HCC tumor cell apoptosis in vitro and in vivo. (A) Level of cleaved caspase-3 in HepG2 and Hep3B cells following infliximab treatment in the presence of effector cells or complement. (B) Cleaved caspase-3 expression following infliximab treatment in HCC xenograft mouse model tissues. Magnification, ×200. Scale bar, 50 µm. *P<0.05, ***P<0.001 vs. mock. HCC, hepatocellular carcinoma; TNF-α, tumor necrosis factor-α.
