Fig. 6. K trans:cis values of (4S)-configured Ac-Xaa-OMe and Ac-Xaa-NMe2 of Flp and Azp derivatives determined by NMR-spectroscopy of 80 mM solutions in D2O (blue) and CDCl3 (green) and difference in the dipole moments (Δμcis–trans) of trans and cis conformers calculated with CHCl3 as solvent at the PBE0-D3-COSMO/def2-TZVP level of theory.
