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. 2018 Jun 7;16(2):723–729. doi: 10.3892/etm.2018.6266

Figure 1.

Figure 1.

The effect of matrine on A549 and H1299 cell proliferation and colony formation. (A) Chemical structure of matrine. Matrine inhibited (B) A549 and (C) H1299 cell proliferation, as determined by the Cell Counting Kit-8 assay. *P<0.05, #P<0.01 vs. 24 h. Matrine inhibited (D) A549 and (E) H1299 cell proliferation, as determined by the EdU assay. Scale bar=100 µm. (F) The ratio of EdU-positive A549 and H1299 cells suppressed by matrine was determined via the EdU assay. *P<0.05. (G and H) Matrine suppressed colony formation in human lung cancer cells. *P<0.05. Data are presented as the mean ± standard deviation (n=3). EdU, 5-ethynyl-2′-deoxyuridine.