Table IV.
Comparison of echocardiographic results and levels of biochemical markers between patients with different severities of PH due to left heart disease in group A prior to and following treatment.
| Mild PH (n=10) | Moderate PH (n=8) | |||||
|---|---|---|---|---|---|---|
| Parameter | Pre-treatment | Post-treatment | P-value | Pre-treatment | Post-treatment | P-value |
| LAD (mm) | 43.5±3.0 | 39.5±3.5 | <0.001 | 48.0±1.3 | 45.1±1.5 | <0.001 |
| LVEDd (mm) | 58.2±3.4 | 53.6±2.4 | <0.001 | 63.4±3.3 | 58.1±2.6 | <0.001 |
| LVEF (%) | 44.1±2.8 | 49.1±3.1 | <0.001 | 35.8±2.6 | 40.6±3.3 | <0.001 |
| PASP (mmHg) | 56.5±2.6 | 46.8±3.6 | <0.001 | 66.0±2.1 | 56.9±2.0 | <0.001 |
| TAPSE (mm) | 17.4±1.4 | 21.2±1.8 | <0.001 | 14.4±1.7 | 18.0±3.1 | <0.001 |
| RVFAC (%) | 38.1±2.0 | 46.5±2.5 | <0.001 | 33.7±2.9 | 40.6±3.5 | <0.001 |
| NT-proBNP (pg/ml) | 3,918.6±283.3 | 2,580.0±104.8 | <0.001 | 5,622.9±681.9 | 3,903.5±603.9 | <0.001 |
| hsCRP (mg/l) | 4.4±1.0 | 1.9±0.5 | <0.001 | 7.3±0.9 | 3.95±0.7 | <0.001 |
Values are expressed as the mean ± standard deviation. LAD, left atrial diameter; LVEDd, left ventricle end diastolic diameter; LVEF, left ventricle ejection fraction; PASP, pulmonary artery systolic pressure; TAPSE, tricuspid annular plane systolic excursion; RVFAC, right ventricular fractional area change; NT-proBNP, N-terminal pro-B-type natriuretic peptide; hsCRP, hypersensitive C-reactive protein; PH, pulmonary hypertension.