Table VI.
Comparison of echocardiographic results and levels of biochemical markers between patients with different severities PH due to left heart disease in group C prior to and following treatment.
| Mild group PH (n=11) | Moderate group PH (n=8) | |||||
|---|---|---|---|---|---|---|
| Parameter | Pre-treatment | Post-treatment | P-value | Pre-treatment | Post-treatment | P-value |
| LAD (mm) | 43.0±3.2 | 40.8±3.7 | <0.001 | 49.4±2.2 | 48.0±2.7 | 0.001 |
| LVEDd (mm) | 58.8±2.6 | 56.3±2.4 | <0.001 | 64.6±2.4 | 62.8±2.4 | <0.001 |
| LVEF (%) | 42.6±1.7 | 44.6±2.4 | 0.001 | 33.9±2.9 | 36.6±4.1 | 0.019 |
| PASP (mmHg) | 56.8±2.3 | 52.8±3.8 | <0.001 | 67.5±1.9 | 65.5±1.9 | <0.001 |
| TAPSE (mm) | 16.8±0.8 | 17.6±0.9 | 0.011 | 13.4±2.1 | 13.9±2.7 | 0.170 |
| RVFAC (%) | 38.7±1.3 | 40.6±1.3 | <0.001 | 31.3±1.5 | 33.3±2.3 | 0.001 |
| NT-proBNP (pg/ml) | 4,008.5±183.0 | 3,525.5±182.0 | <0.001 | 5,908.5±1,017.4 | 5,223.4±1,024.0 | <0.001 |
| hsCRP (mg/l) | 3.3±0.6 | 2.8±0.8 | 0.003 | 7.7±1.9 | 7.4±1.8 | 0.186 |
Values are expressed as the mean ± standard deviation. LAD, left atrial diameter; LVEDd, left ventricle end diastolic diameter; LVEF, left ventricle ejection fraction; PASP, pulmonary artery systolic pressure; TAPSE, tricuspid annular plane systolic excursion; RVFAC, right ventricular fractional area change; NT-proBNP, N-terminal pro-B-type natriuretic peptide; hsCRP, hypersensitive C-reactive protein; PH, pulmonary hypertension.