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. 2018 May 24;16(2):585–594. doi: 10.3892/etm.2018.6217

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Copyright: © Shu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Levels of inflammatory factors in the plasma of pregnant rats in each group at the end of pregnancy (GD20) were measured using the BioLegend multi-factor flow assay. (A) Circulating MCP-1, (B) IL-17A, (C) TNF-α and (D) IL-1β levels. **P<0.05 vs. control group. Values are expressed as the mean ± standard deviation. Groups: 9D LL, rats treated with low-dose L-NAME (40 mg/kg body weight/day) starting from GD 9; 9D ML, rats treated with medium-L-NAME (75 mg/kg body weight/day) starting from GD 9; 9D HL, rats treated with high-dose L-NAME (125 mg/kg body weight/day) starting from GD 9; 10D LL, rats treated with low-dose L-NAME (40 mg/kg body weight/day) starting from GD 10; 10D ML, rats treated with medium-L-NAME (75 mg/kg body weight/day) starting from GD 10; 10D HL, rats treated with high-dose L-NAME (125 mg/kg body weight/day) starting from GD 10; control, normal pregnancy group. GD, gestational day; L-NAME, N-nitro-L-arginine methyl ester; TNF, tumor necrosis factor; IL, interleukin; MCP, monocyte chemoattractant protein.