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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Auton Neurosci. 2018 Jun 8;213:51–59. doi: 10.1016/j.autneu.2018.05.009

Table 1. Previously Reported Clinical and Histopathological effects of S. Typhimurium.

challenged Data in this table are summarized from a previously reported study.(Boyer et al. 2015) Fecal consistency was scored on a 4 point scale by an individual blinded to the study design (1= no diarrhea; 4= severe, profuse diarrhea). Histopathology scoring was performed as previously reported. Villus blunting was scored on a 5 point scale with 0 = 1:4 crypt to villus height and 4 = no villus present. Villus fusion and lymphoid depletion were scored on a 4 point scale with 0 = normal and 3 = severe. n=5–6 per group. pvalues generated by two tailed students t-test. For significance, y=yes; n=no.

Control S. typhimurium challenged P value
Fecal Score 1.20 3.33 0.0012
    Rectal Temperature(°C) 39.70 40.64 0.0238
        Histopathology Scores Villus Blunting 0.00 2.20 0.0172
Villus Fusion 0.00 1.40 0.0479
Lymphoid Depletion 0.20 2.00 0.0063