Table 3.
Correlation of CAG repeat length with age of onset and disease severity
| Variable | R Valuea | P Valueb |
|---|---|---|
| Age of onset | −0.760 | 0.0001 |
| ICARS | −0.203 | 0.4180 |
| Posture score | −0.210 | 0.4020 |
| Kinetic score | −0.278 | 0.2630 |
| Speech score | +0.256 | 0.3060 |
| Oculomotor score | +0.263 | 0.2920 |
| FGA score | +0.030 | 0.9070 |
| SCAFI | ||
| Average 8‐m walking speed | −0.197 | 0.4490 |
| Average 9‐hole peg test time, RUL | +0.078 | 0.7730 |
| Average 9‐hole peg test time, LUL | +0.214 | 0.4270 |
| Average 9‐hole peg test time | +0.138 | 0.6090 |
| Average PATA read‐outs in 10 s | +0.241 | 0.3510 |
Abbreviations: ICARS, International Cooperative Ataxia Rating Scale; FGA, Functional Gait Assessment; SCAFI, spinocerebellar ataxia functional index; RUL, right upper limb; LUL, left upper limb.
a
The correlation coefficient (R) was calculated using Pearson's correlation coefficient. An R value of −0.76 indicates a high negative correlation.
b
P values < 0.05 indicate statistical significance.