Table 3.

Longitudinal associations between shift work at baseline and diurnal cortisol pattern at follow-up (N = 70)

Cortisol slope	Model I	Model II	Model III	Model IV	Model V
Shift work: No	0	0	0	0	0
Shift work: Yes	−0.09 (− 0.18, − 0.01)*	−0.11 (− 0.20, − 0.02) *	−0.11 (− 0.20, − 0.02)*	−0.12 (− 0.21, − 0.04)**	−0.12 (− 0.21, − 0.03)**
Total cortisol AUC	Model I	Model II	Model III	Model IV	Model V
Shift work: No	0	0	0	0	0
Shift work: Yes	5.36 (0.20, 10.52) *	6.19 (1.13, 11.25) *	6.33 (1.25, 11.41) *	6.71 (1.55, 11.86) *	6.64 (1.48, 11.79) *

Linear regression, β (95% CI), *p < 0.05, **p < 0.01

Model I: adjustment for biological factors (age and gender)

Model II: Model I + additional adjustment for work factors (professional tenure and working hours) at baseline

Model III: Model II + additional adjustment for family factors (partnership and children) at baseline

Model IV: Model III + additional adjustment for behavioral factors (smoking, risky alcohol use, physical activity, overweight and obesity) at baseline

Model V: Model IV + additional adjustment for cortisol secretion at baseline