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. 2018 Aug 13;18:114. doi: 10.1186/s12935-018-0612-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Verification efficiency of up (a) or down-regulated (b) miR-524 expression in MG-63 and 143B cell lines by qRT-PCR. After overexpression of miR-524 in MG-63 (c) and 143B cells (d), proliferation is significantly enhanced. After down-regulation of miR-524 expression in MG-63 (e) and 143B cells (f), proliferation is significantly decreased. g After down-regulation of miR-524 expression in MG-63 and 143B cells, apoptosis is significantly increased (***P < 0.001, **P < 0.01, *P < 0.05)