Table 4.

Findings of the joinpoint regression for IPD by age group

Age group	Joinpoint	Years Range	APC (95% CI)	p-value
All age groups	No JP	2000–2015	0.7 (-0.6; 2.1)	0.3
<1 year	2004	2000–2004	15.5 (-25.5; 78.9)	0.5
		2004–2015	-16.7 (-28; -3.6)	< 0.0001
1–4 years	No JP	2000–2015	-7 (-13.7; 0.2)	0.1
5–9 years	No JP	2000–2015	0.8 (-9.5; 12.2)	0.9
10–14 years	2002	2000–2002	81.9 (79.6; 84.3)	< 0.0001
	2009	2002–2009	-20.4 (-20.6; -20.2)	< 0.0001
	2012	2009–2012	99 (96.4; 101.6)	< 0.0001
		2012–2015	-50.1 (-50.4; -49.7)	< 0.0001
15–24 years	2003	2000–2003	95.2 (-50.5; 670.3)	0.3
		2003–2015	-13.4 (-22.5; -3.3)	< 0.0001
25–64 years	No JP	2000–2015	0.8 (-1.8; 3.5)	0.5
≥65 years	No JP	2000–2015	1.7 (-0.5; 3.8)	0.1

IPD invasive pneumococcal diseases, APC annual percent change, CI confidence interval, JP joinpoint