Fig. 11.

Microarray gene expression analysis of M1, M2, and M1/M2 mixed microglia gene sets at 1 day after MPTP treatment. a Scatter plots. The X- and Y-axis values are log10 scale-normalised signals. b Enrichment plots (green curve) show the running sum of enrichment score (ES) for each gene set. The score at the peak of the plots is the ES for each gene set. The black bars show where the members of the gene set appear in the ranked list of genes. A predominance of black bars to the left or right side indicates that most genes are upregulated in MPTP-treated WT mice or MPTP-treated Cx30 KO mice, respectively