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. 2018 Aug 13;37:189. doi: 10.1186/s13046-018-0855-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — MKRN2 protein levels are negatively correlated with the migration and invasion of NSCLC cells. a Transwell assays were performed to assess cell migration and invasion in the context of MKRN2 overexpression and downregulation. MKRN2 overexpression in A549 and H1299 cells inhibited cell migration and invasion, and MKRN2 knockdown enhanced cell migration and invasion. *P < 0.05; **P < 0.01. b, c The effects of MKRN2 levels on the expression of proteins associated with cell migration and invasion in transfected b A549 and c H1299 cells. Relative quantification analysis was based on grayscale values. *P < 0.05; **P < 0.01