Table 3.
Summary of genetic variants used as instrumental variables in summary statistics approach
| ID | Gene | Effect allele | Chromosome | Beta (25-OHD) | Se (25-OHD) | Beta (CRC) | Se (CRC) |
|---|---|---|---|---|---|---|---|
| rs10741657 | CYP2R1 | A | 11 | 0.0312 | 0.0022 | 0.0162 | 0.0135 |
| rs10745742 | AMDHD1 | T | 12 | 0.0167 | 0.0022 | −0.0049 | 0.0138 |
| rs12785878 | NADSYN1/ DHCR7 | T | 11 | 0.0361 | 0.0022 | −0.0097 | 0.016 |
| rs17216707 | CYP24A1 | T | 20 | 0.0262 | 0.0027 | 0.0138 | 0.0173 |
| rs3755967 | GC | C | 4 | 0.0893 | 0.0023 | −0.0154 | 0.0148 |
| rs8018720 | SEC23A | G | 14 | 0.0164 | 0.0029 | −0.0163 | 0.0176 |
Beta regression coefficients of GWAS meta-analysis, se standard error, CRC colorectal cancer