Table 5.
Survival analyses using binary logistic regression predicting likelihood of Mild Cognitive Impairment (MCI) stability (coded as 1) (n = 64)
| Variable | B | SE | P Value | OR | 95% CI |
|---|---|---|---|---|---|
| Model 1 | |||||
| Follow-up 1 | −1.24 | 0.66 | < 0.001 | 0.289 | 0.153–0.546 |
| Follow-up 2 | −1.85 | 0.59 | < 0.001 | 0.157 | 0.065–0.379 |
| Follow-up 3 | −1.78 | 0.56 | < 0.001 | 0.168 | 0.064–0.436 |
| Motivational abilities a | −0.53 | 0.36 | 0.040 | 0.587 | 0.353–0.976 |
| Model 2 | |||||
| Follow-up 1 | −0.52 | 0.92 | 0.572 | 0.596 | 0.099–3.582 |
| Follow-up 2 | −1.85 | 1.05 | 0.078 c | 0.157 | 0.020–1.233 |
| Follow-up 3 | −0.76 | 1.01 | 0.454 | 0.468 | 0.064–3.413 |
| Motivational abilities a | −0.65 | 0.33 | 0.052 c | 0.524 | 0.273–1.005 |
| Age | 0.33 | 0.33 | 0.323 | 1.389 | 0.725–2.661 |
| Sex (0 = male, 1 = female) | −0.53 | 0.60 | 0.376 | 0.589 | 0.182–1.902 |
| Children (number) | 0.67 | 0.30 | 0.028 | 1.954 | 1.076–3.547 |
| Model 3 | |||||
| Follow-up 1 | −1.07 | 1.02 | 0.294 | 0.345 | 0.047–2.519 |
| Follow-up 2 | −2.34 | 1.13 | 0.038 | 0.096 | 0.011–0.880 |
| Follow-up 3 | −1.27 | 1.10 | 0.247 | 0.280 | 0.032–2.414 |
| Motivational abilities a | −0.74 | 0.35 | 0.036 | 0.477 | 0.239–0.952 |
| Age | 0.13 | 0.36 | 0.727 | 1.135 | 0.558–2.308 |
| Sex (0 = male, 1 = female) | −0.54 | 0.60 | 0.372 | 0.584 | 0.179–1.902 |
| Children (number) | 0.73 | 0.32 | 0.022 | 2.082 | 1.109–3.908 |
| Executive function b | 0.02 | 0.01 | 0.196 | 1.016 | 0.992–1.042 |
| Model 4 | |||||
| Follow-up 1 | −0.11 | 1.89 | 0.955 | 0.899 | 0.022–36.773 |
| Follow-up 2 | −1.46 | 1.91 | 0.446 | 0.233 | 0.005–9.854 |
| Follow-up 3 | −0.35 | 1.93 | 0.854 | 0.702 | 0.016–30.550 |
| Motivational abilities a | −0.66 | 0.34 | 0.051 c | 0.515 | 0.264–1.003 |
| Age | 0.31 | 0.34 | 0.374 | 1.358 | 0.692–2.667 |
| Sex (0 = male, 1 = female) | −0.58 | 0.64 | 0.360 | 0.559 | 0.161–1.940 |
| Children (number) | 0.70 | 0.32 | 0.031 | 2.003 | 1.066–3.763 |
| Education (years) | −0.03 | 0.11 | 0.804 | 0.973 | 0.781–1.212 |
| Model 5 | |||||
| Follow-up 1 | −0.07 | 0.96 | 0.940 | 0.930 | 0.141–6.120 |
| Follow-up 2 | −1.36 | 1.09 | 0.213 | 0.257 | 0.030–2.181 |
| Follow-up 3 | −0.17 | 1.07 | 0.876 | 0.845 | 0.103–6.941 |
| Motivational abilities a | −0.63 | 0.33 | 0.060 c | 0.534 | 0.277–1.028 |
| Age | 0.16 | 0.38 | 0.684 | 1.169 | 0.551–2.479 |
| Sex (0 = male, 1 = female) | −0.45 | 0.62 | 0.470 | 0.638 | 0.188–2.161 |
| Children (number) | 0.73 | 0.33 | 0.024 | 2.084 | 1.100–3.947 |
| MCI amnestic (0 = amnestic, 1 = non-amnestic) | −1.47 | 0.62 | 0.018 | 0.230 | 0.068–0.773 |
| Model 6 | |||||
| Follow-up 1 | −0.79 | 1.45 | 0.584 | 0.452 | 0.026–7.749 |
| Follow-up 2 | −1.35 | 1.64 | 0.408 | 0.258 | 0.010–6.381 |
| Follow-up 3 | −0.14 | 1.58 | 0.931 | 1.146 | 0.052–25.359 |
| Motivational abilities a | −0.50 | 0.49 | 0.303 | 0.606 | 0.233–1.574 |
| Age | 0.78 | 0.52 | 0.135 | 2.181 | 0.784–6.064 |
| Sex (0 = male, 1 = female) | −0.38 | 0.92 | 0.683 | 0.687 | 0.113–4.163 |
| Children (number) | 0.90 | 0.48 | 0.060 c | 2.455 | 0.963–6.255 |
| Cardiovascular risk factors | −3.29 | 1.59 | 0.038 | 0.037 | 0.002–0.837 |
The bold values indicate a statistically significant correlation with a p-value less than 0.05
B coefficient, CI confidence interval, MCI mild cognitive impairment, OR odds ratio, p level of significance, SE standard error
a Composite measure including informant-rated motivational abilities at baseline (t1)
b Interference score of the Stroop Color-Word Test
c marginally significant