Fig. 3.

MSCs alleviated chronic colitis-associated hepatobiliary disorders. The DSS + vehicle group showed more severe hepatobiliary disorders compared to that of the control group, while MSCs ameliorated hepatobiliary disorders associated with chronic colitis. a Representative sections samples of liver (H&E and MT staining; original magnifications, × 200). b Histological score (^aP < 0.05 vs. the DSS + vehicle group; ^bP < 0.05 vs. the control group). c, d Liver function, ALT and AST levels in the DSS + vehicle group were increased and ALB level were lowered compared to that of the control group. ALT and AST levels in the DSS + MSCs group were significantly lower and ALB levels were increased (^aP < 0.05 vs. the DSS + vehicle group; ^bP < 0.05 vs. the control group). TBIL and DBIL levels were not changed (^aP > 0.05 vs. the DSS + vehicle group; ^bP > 0.05 vs. the control group). Data were expressed as mean ± SD