Table 1.
Demographic data, baseline characteristics, and patient outcomes. Data are presented as mean (standard deviation), median (quartiles), and frequency (%)
| Control group (n = 21) | Dexmedetomidine group (n = 21) | P value | |
|---|---|---|---|
| Age (years) | 32 (5)a | 29 (4) | 0.05 |
| BMI (kg/m2) | 45 (3)a | 48 (4) | 0.03 |
| Smoking | 5 (25%) | 6 (29%) | 0.95 |
| COPD, emphysema | 0(%) | 0 (0%) | 1 |
| FVC (% predicted) | 65 (61,67) | 62 (60,66) | 0.28 |
| FEV1/FVC (%) | 81 (78,84) | 80 (77,83) | 0.33 |
| Baseline PaCO2 (mmHg) | 42 (7) | 39 (5) | 0.1 |
| Surgical duration | 113 (19) | 109 (18) | 0.5 |
| Intraoperative fluids | 844 (101) | 831 (103) | 0.7 |
| Blood loss | 238 (76) | 258 (78) | 0.4 |
| Postoperative complications | |||
| - ICU admission | 3 (14%) | 2 (10%) | 0.9 |
| - Invasive ventilation | 2 (10%) | 1 (5%) | 1 |
| - Anastomotic leakage | 0 (0%) | 0 (0%) | 1 |
| - Bleeding | 0 (0%) | 0 (0%) | 1 |
| - Pneumonia | 0 (0%) | 0 (0%) | 1 |
| - 28-day death | 0 (0%) | 0 (0%) | 1 |
| POSS | 2 (1,2) | 2 (1,2) | 1 |
BMI Body mass index, COPD Chronic obstructive pulmonary disease, FEV1 Forced expiratory volume in the first second, FVC Forced vital capacity, ICU intensive care unit, POSS Pasero opioid-induced sedation scale, P/F ratio PaO2/fraction of inspired oxygen
adenotes statistical significance between both groups