Table 3.
The relative expression of target mRNAs in the control, cisplatin, and 0.64 mg/mL SPS groups
Groups | Bcl-2 | COX-2 | Bax | Cleaved caspase-3 |
---|---|---|---|---|
Control (24 h) | 0.713 ± 0.031 | 0.638 ± 0.048 | 0.185 ± 0.043 | 0.262 ± 0.081 |
Control (48 h) | 0.720 ± 0.196 | 0.592 ± 0.005 | 0.166 ± 0.121 | 0.321 ± 0.021 |
Control (72 h) | 0.693 ± 0.232 | 0.799 ± 0.923 | 0.203 ± 0.056 | 0.301 ± 0.044 |
Cisplatin (24 h) | 0.585 ± 0.055 | 0.513 ± 0.023* | 0.481 ± 0.011* | 0.477 ± 0.021* |
Cisplatin (48 h) | 0.451 ± 0.060* | 0.416 ± 0.019* | 0.566 ± 0.035* | 0.681 ± 0.046* |
Cisplatin (72 h) | 0.281 ± 0.026* | 0.264 ± 0.032* | 0.762 ± 0.055* | 0.872 ± 0.065* |
SPS (24 h) | 0.423 ± 0.055* | 0.408 ± 0.023* | 0.314 ± 0.011* | 0.585 ± 0.034* |
SPS (48 h) | 0.345 ± 0.060* | 0.222 ± 0.019* | 0.426 ± 0.035 | 0.822 ± 0.081* |
SPS (72 h) | 0.201 ± 0.026* | 0.118 ± 0.032* | 0.582 ± 0.055* | 1.031 ± 0.092* |
SPS safflower polysaccharide. *P < 0.05 compared with the control group