Table 4.
The relative expression of the target proteins in the control, cisplatin, and 0.64 mg/mL SPS groups
Groups | Bcl-2 | COX-2 | Bax | Cleaved caspase-3 |
---|---|---|---|---|
Control (24 h) | 0.723 ± 0.121 | 0.918 ± 0.095 | 0.282 ± 0.164 | 0.464 ± 0.091 |
Control (48 h) | 0.719 ± 0.196 | 0.922 ± 0.132 | 0.283 ± 0.053 | 0.460 ± 0.021 |
Control (72 h) | 0.733 ± 0.198 | 0.899 ± 0.210 | 0.290 ± 0.026 | 0.465 ± 0.018 |
Cisplatin (24 h) | 0.442 ± 0.113* | 0.661 ± 0.066* | 0676 ± 0.103* | 0.679 ± 0.093* |
Cisplatin (48 h) | 0.393 ± 0.045* | 0.458 ± 0.072* | 0.867 ± 0.064* | 0.863 ± 0.123* |
Cisplatin (72 h) | 0.107 ± 0.062 | 0.237 ± 0.069 | 0.916 ± 0.093* | 0.991 ± 0.133* |
SPS (24 h) | 0.513 ± 0.101* | 0.795 ± 0.135* | 0.740 ± 0.0858 | 0.602 ± 0.076* |
SPS (48 h) | 0.392 ± 0.083* | 0.590 ± 0.099* | 0.920 ± 0.083* | 0.764 ± 0.063* |
SPS (72 h) | 0.206 ± 0.106* | 0.435 ± 0.021* | 1.832 ± 0.925* | 0.948 ± 0.089* |
SPS safflower polysaccharide. *P < 0.05 compared with the control group