Table 2.
Findings of both groups according to kidney function in patients with GUTB
| Variables | Normal kidney function group (n = 45) | CKD group (n = 11) | Total (n = 56) | p |
|---|---|---|---|---|
| Diagnosis | ||||
| Positivity of urine AFB stain | 3/41 (7.3) | 3/10 (30.0) | 6/51 (11.8) | 0.081 |
| Positivity of urinary TB culture | 17/38 (44.7) | 7/10 (70.0) | 24/48 (50.0) | 0.155 |
| Positivity of urine TB PCR study | 17/36 (47.2) | 8/9 (88.9) | 25/45 (55.6) | 0.030 |
| Histopathologic diagnosis | 24 (53.3) | 6 (54.5) | 30/55 (53.6) | 0.741 |
| Laboratory data | ||||
| White blood cell (/μl) | 6880 (5650–7890) | 6520 (5580–8395) | 6695 (5580–7915) | 0.699 |
| Hemoglobin (g/dl) | 12.5 ± 1.8 | 11.7 ± 1.7 | 12.3 ± 1.8 | 0.174 |
| Platelet (103/μl) | 259.0 ± 80.5 | 263.2 ± 121.2 | 259.9 ± 89.1 | 0.893 |
| ESR (mm/hr) | 46.9 ± 23.8 | 82.5 ± 53.0 | 53.4 ± 30.7 | 0.145 |
| Blood urea nitrogen (mg/dl) | 13.9 (10.5–16.9) | 17.8 (15.4–27.8) | 14.4 (11.6–17.6) | 0.006 |
| Creatinine (mg/dl) | 0.9 (0.8–1.0) | 1.4 (1.1–1.8) | 1.0 (0.8–1.1) | 0.002 |
| eGFR (MDRD) | 78.1 ± 16.5 | 49.4 ± 23.4 | 75.8 ± 23.5 | 0.002 |
| eGFR (MDRD) after 1 year | 82.7 ± 16.5 | 35.1 ± 18.1 | 72.8 ± 25.6 | < 0.001 |
| Acute renal failure | 3 (6.7) | 7 (63.6) | 10 (17.9) | < 0.001 |
| Glucose (mg/dl) | 98.0 (89.0–108.0) | 104.0 (99.5–121.5) | 100.0 (90.0–112.0) | 0.075 |
| Albumin (g/dl) | 4.4 (3.9–4.6) | 3.8 (3.5–4.2) | 4.3 (3.8–4.5) | 0.102 |
| CRP (mg/dl) | 10.2 (3.7–38.2) | 45.3 (19.3–65.5) | 15.0 (5.0–44.2) | 0.090 |
| Microscopic hematuria | 19 (42.2) | 9 (81.8) | 28 (50.0) | 0.019 |
| Gross hematuria | 14 (31.1) | 5 (45.5) | 19 (33.9) | 0.481 |
| Pyuria | 29 (64.4) | 8 (72.7) | 37 (66.1) | 0.732 |
| Proteinuria | 6 (13.3) | 5 (45.5) | 11 (19.6) | 0.029 |
Bold values indicate statistically significant differences
Data were presented as mean ± SD, number (percentage) or median (IQR). All data are based on the results at the time of diagnosis except for ‘eGFR after 1 year’
GUTB genitourinary tuberculosis, CKD chronic kidney disease, AFB acid-fast bacilli, TB tuberculosis, PCR polymerase chain reaction, ESR erythrocyte sedimentation rate, eGFR estimated glomerular filtration rate, MDRD Modification of Diet in Renal Disease study equation, CRP c-reactive protein, SD standard deviation, IQR interquartile range