Table 2.
Study author (year) [reference] | Groups | Age (years) Mean (SD) |
Sex F/M | N | Design | Diagnosis | Involved side Unilateral/bilateral | Athlete/nonathlete | Duration of symptoms (months) Mean (SD, range) |
Cointervention | Follow up time point | Outcome results | Fund or grant§ | MQ score* |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chen (2014) [51] | EG: ESWT + MSE | 63.0 (7.4)‡ | 102/18‡ | 30 | RCT, DB | Popliteal cyamella | NR | Nonathlete | 10–144‡ | None | Baseline | VASb,c; ROMb,c | Funded | 7/10 |
CG 1: USD + MSE | 30 | Posttest: ≤1, 6 months | Lequesne’s indexb,c | |||||||||||
CG 2: MSE | 30 | |||||||||||||
CG 3: Non-ESWT† | 30 | |||||||||||||
Geng (2017) [90] | EG: ESWT + APT | 35.9 (10.2)‡ | 19/41‡ | 30 | RCT | CPT | NR | Nonathlete | 4.7 (2.8) ‡ | None | Baseline | VASa,b,c; PTTa,b,c | Funded | 6/10 |
CG: CT | 30 | Posttest: 1 month | 4-point Likert scalec | |||||||||||
Guan (2015) [80] | EG: ESWT | 45.5 (20–80)‡ | 91/55‡ | 73 | RCT | PAT | 128/18‡ | Nonathlete | 12.5 (6–36)‡ | None | Baseline | VASa,b,c | NR | 6/10 |
CG: CT | 73 | Posttest: 6 months | ||||||||||||
Huang (2017) [88] | EG: ESWT | 22.0 (3.0) | 0/31 | 31 | RCT | CPT | 28/3 | Athlete | 12.0 (6–24) | None | Baseline | VASa,b,c; VISA-Pa,b,c | Funded | 6/10 |
CG: CT | 21.0 (3.0) | 0/30 | 30 | 29/1 | 11.0 (6–20) | Posttest: 1, 3, 12 months | 4-point Likert scalec | |||||||
Jiang (2016) [81] | EG: ESWT | 35.7 (9.1) | 24/16 | 40 | RCT | CPT | 40/0 | Nonathlete | 4.2 (3.9) | PT | Baseline | VASa,b,c; PIb,c | NR | 6/10 |
CG: Non-ESWT† | 34.4 (10.7) | 21/15 | 36 | 36/0 | 4.7 (4.4) | Pain medication | Posttest: ≤1, 2 weeks | KOS-ADLSa,b,c | ||||||
Khosrawi (2017) [48] | EG: ESWT | 49.4 (7.8) | 16/4 | 20 | RCT, SB | PAT | NR | Nonathlete | > 3 months‡ | STE | Baseline | VASa,b,c; MPQa,b,c | Funded | 8/10 |
CG: Sham ESWT | 50.2 (8.1) | 15/5 | 20 | Pain medication | Posttest: ≤1, 2 months | |||||||||
Liu (2016) [82] | EG: ESWT | 22.1 (1.5) | 22/28 | 50 | RCT, SB | CPT | 50/0 | Athlete | 4.9 (1.3, 3–6) | APT | Baseline | VASa,b,c; VISA-Pa,b,c | Funded | 6/10 |
CG: Iontophoresis | 22.2 (1.3) | 23/27 | 50 | 50/0 | 5.0 (1.1, 3–6) | Massage | Posttest: ≤1, 3, 6, 12 months | 4-point RMSc | ||||||
Taunton (2003) [83] | EG: ESWT | 23–52‡ | 5/5 | 10 | RCT, SB | CPT | NR | Athlete | > 3 months ‡ | None | Baseline | VISA-Pa,b,c | Funded | 5/10 |
CG: Sham ESWT | 5/5 | 10 | Posttest: ≤1, 3 months | Vertical jump testb,c | ||||||||||
Thijs (2017) [84] | EG: ESWT | 30.5 (8.0) | 8/14 | 22 | RCT, DB | CPT | NR | Nonathlete | 16.3 (18.2, 3–78) | ET exercise | Baseline | VASa,b; VISA-Pa,b | NR | 9/10 |
CG: Sham ESWT | 27.3 (5.2) | 6/24 | 30 | 24.9 (31.6, 3–125) | Posttest: ≤1, 3, 6 months | 6-point Likert scale | ||||||||
Vetrano (2013) [85] | EG: ESWT | 26.8 (8.5) | 6/17 | 23 | RCT, SB | CPT | 23/0 | Athlete | 17.6 (20.2) | STE | Baseline | VASa,b,c; VISA-Pa,b,c | NR | 7/10 |
CG: PRP | 26.9 (9.1) | 3/20 | 23 | 23/0 | 18.9 (19.1) | Posttest: 2, 6, 12 months | MBSa,b,c | |||||||
Wang (2014) [86] | EG: ESWT | 28.3 (7.4) | 5/21 | 26 | RCT, SB | ACL reconstruction | 26/0 | Nonathlete | 21.4 (22.5, 1–72) | PT | Baseline | LFSa,b,c | Funded | 8/10 |
CG: Non-ESWT† | 27.7 (7.7) | 6/21 | 27 | 27/0 | 15.4 (21.9, 1–84) | Posttest: 12, 24 months | IKDC scorea,b | |||||||
Weckström (2016) [52] | EG: ESWT | 23.7 (2.0) | 6/14 | 11 | RCT | ITBS | NR | Nonathlete | 60.4 (53.7) | MSE | Baseline | 11-point NRSb; | NR | 7/10 |
CG: CT | 24.2 (2.2) | 7/13 | 13 | 42.3 (65.1) | STE | Posttest: 1, 2, 12 months | Treadmill test | |||||||
Wu (2009) [91] | EG: ESWT | 15.9 (11–19) | 9/21 | 30 | RCT | OSD | NR | Athlete | 3–36 | None | Baseline | VASa,b,c; MPQa,b,c | NR | 6/10 |
CG: USD | 16.5 (14.–19) | 7/23 | 30 | 3–36 | Posttest: 0, 3 months | 3-point Likert scalec | ||||||||
Wu (2016) [89] | EG: ESWT | 26.0 (19–38)‡ | 7/55‡ | 31 | RCT | ACL injury | 31/0 | Nonathlete | 3.8 (1–12)‡ | PT | Baseline | VASa,b,c | NR | 6/10 |
CG: Non-ESWT† | 31 | 31/0 | Posttest: ≤1 month | 4-point Likert scalec | ||||||||||
Yang (2007) [16] | EG: ESWT | 34.0 (7.4) | 6/22 | 28 | RCT | PTKS | 28/0 | Nonathlete | 6.0 (5.3) | MSE | Baseline | VASa,b,c; ROMa,b,c | NR | 5/10 |
CG: CPM | 33.0 (8.4) | 9/20 | 29 | 29/0 | 6.0 (3.3) | Posttest: ≤1 month | 4-point Likert scalec | |||||||
Zhang (2016) [92] | EG: ESWT | 48.0 (4.6) | 10/8 | 18 | RCT, SB | Traumatic synovitis | 18/0 | Nonathlete | 1–2 | APT; MSE | Baseline | VASa,b,c; ROMa,b,c; | Funded | 6/10 |
CG: Non-ESWT† | 50.0 (5.8) | 11/7 | 18 | 18/0 | 1–2 | Posttest: 2, 4, 6 weeks | Swellinga,b,c; LFSa,b,c 4-point Likert scale | |||||||
Zhang (2017) [17] | EG: ESWT | 34.8 (5.6) | 7/21 | 28 | RCT | PTKS | 28/0 | Nonathlete | 4.7 (2.3) | PT | Baseline | VASa,b,c; ROMa,b,c; | NR | 6/10 |
CG: Non-ESWT† | 35.5 (4.9) | 9/17 | 26 | 26/0 | 4.3 (2.6) | Posttest: 0 month | HSSa,b,c; 4-point Likert scale | |||||||
Zhou (2015) [53] | EG: ESWT | 25.0 (18–30)‡ | 30/30‡ | 30 | RCT | IPFP injury | 50/10 | Athlete | 24 (1–48)‡ | None | Baseline | VASa,b,c; | NR | 6/10 |
CG: APT | 30 | Posttest: ≤1 month | 4-point Likert scalec | |||||||||||
Zwerver (2011) [87] | EG: ESWT | 24.2 (5.2) | 11/20 | 31 | RCT, DB | CPT | 18/13 | Athlete | 7.3 (3.6) | Sports participation | Baseline | VAS a,b; VISA-P a,b; | Funded | 9/10 |
CG: Sham ESWT | 25.7 (4.5) | 10/21 | 31 | 13/18 | 8.1 (3.8) | Medical treatment | Posttest: ≤1, 3, 6 months | Knee-loading pain test |
*Assessed using the 10-point PEDro classification scale
†No application of shock wave treatment
‡Value of total sample
§Details of the funding information of the studies are presented in Additional file 10: Table S3
aSignificant improvements in the control group compared with baseline (P < 0.05)
bSignificant improvements in the experimental group compared with baseline (P < 0.05)
cSignificant between-group difference for ESWT compared with control (P < 0.05)
MQ methodological quality, EG experimental group, CG control group, ESWT extracorporeal shock wave therapy, RCT randomized controlled trial, QRCT Quasi-randomized controlled trial, DB double blind, VAS visual analog scale, NR not reported, ET eccentric training, VISA-P Victorian Institute of Sport Assessment-Patella, PRP platelet-rich plasma, PTKS posttraumatic knee stiffness, USD ultrasound diathermy, MSE muscular strengthening exercise, APT acupuncture therapy, LPNIR-LI linear polarized near-infrared light irradiation, CT conservative treatment, STE stretching exercise, ITBS iliotibial band syndrome, OSD Osgood–Schlatter disease, CPT chronic patellar tendinopathy, PTT patellar tendon thickness, PT physiotherapy, PAT pes anserine tendinopathy, MPQ McGill pain questionnaire, PI patellar intumesce, KOS-ADLS Knee Outcome Survey-activities of Daily Living Scale, ACL anterior cruciate ligament, LFS Lysholm functional score, MBS Modified Blazina scale, IKDC International Knee Documentation Committee, CPM continuous passive motion, LCSI local corticosteroid injection, HSS Hospital for Special Surgery Knee score, IPFP infrapatellar fat pad, ROM range of motion