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. 2018 Aug 3;19:27. doi: 10.1186/s12865-018-0262-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — WiDr-injected SCID mice were treated with NaB, NK-92MI, anti-CEA CAR NK-92MI, and anti-CEA CAR NK-92MI + NaB for 15 days. Tumours were measured at Days 0, 4, 9, 12 and 15 after treatment. a Tumour growth curves show that the anti-CEA CAR NK-92MI and anti-CEA CAR NK-92MI + NaB treatments inhibit tumour growth significantly better than the control, NaB alone, or NK-92MI alone. b Treatment with NaB or NK-92MI did not significantly inhibit tumour growth relative to the control. Tumour size was significantly reduced by treatment with anti-CEA CAR NK-92MI and even more so in response to the combination of anti-CEA CAR NK-92MI and NaB