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. 2018 Aug 3;37:182. doi: 10.1186/s13046-018-0854-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — RIF1 promotes EOC cell growth in vitro. a-d Efficiency of RIF1 knockdown (RIF1 KD) by two shRNAs and RIF1 overexpression (RIF1 over) in OVCAR3 and A2780 cells was verified by real-time qPCR (a and b) and western blot (c and d). e and f Influence of RIF1 knockdown and overexpression on the cell viability of OVCAR3 (e) and A2780 (f) cells measured by the MTS assay. g and h Effect of RIF1 knockdown and overexpression on colony formation was measured in OVCAR3 and A2780 cells. Data were presented as mean ± SD of three independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001