. 2018 Aug 3;18:782. doi: 10.1186/s12885-018-4699-5

Table 1.

Subscales of health-related quality of life by patients’ characteristics at baseline and responses to TKI therapy within 1 year

Variable	No (%)	PF		RP		BP		GH		PCS		VT		SF		RE		MH		MCS
Variable	No (%)	Median	P	Median	P	Median	P	Median	P	Median	P	median	P	Median	P	Median	P	Median	P	Meidan	P
Gender			0.61		0.75		0.58		0.44		0.84		0.36		*0.024*		0.18		0.91		0.087
Male	35 (59.3)	56.46		48.15		50.24		52.62		49.67		58.61		52.53		54.81		58.94		54.13
Female	24 (40.7)	56.46		51.88		50.25		55.84		51.14		61.00		59.55		54.81		58.06		58.76
Age			0.056		0.66		0.55		0.78		0.62		0.96		0.73		0.14		0.42		0.85
< 40 years	33 (55.9)	56.46		48.15		54.15		56.58		50.29		58.61		59.55		54.81		57.18		56.54
≥ 40 years	26 (44.1)	53.94		51.88		46.34		53.86		50.31		58.61		52.53		49.67		58.94		55.40
Education			0.36		0.85		0.40		0.54		0.64		0.19		0.66		0.14		*0.026*		*0.030*
≥ Bachelor degree	24 (40.7)	56.46		48.15		54.15		55.35		51.94		62.20		52.53		54.81		60.70		52.60
< Bachelor degree	35 (59.3)	56.46		55.60		46.34		55.10		49.67		58.61		59.55		54.81		55.42		59.58
TKI used			0.52		0.71		0.98		*0.042*		0.38		0.87		0.49		0.49		0.23		0.40
Imatinib	31 (52.5)	56.46		55.60		54.15		52.62		49.01		58.61		52.53		54.81		58.94		57.29
Nilotinib	28 (47.5)	57.73		48.15		50.24		58.32		52.21		59.81		59.55		54.81		57.18		52.93
Sokal risk			0.63		0.31		0.67		0.48		0.17		0.29		0.32		0.84		0.47		0.99
Low	28 (47.5)	56.46		48.15		48.29		54.60		48.35		58.61		52.53		54.81		58.94		56.07
Intermediate / High	18 (30.5) /13 (22.0)	56.46		55.60		54.15		55.10		52.52		58.61		59.55		54.81		57.18		56.54
Response at 3 months			0.35		0.26		0.30		0.36		0.20		0.71		0.94		0.41		0.83		0.80
Optimal	44 (74.6)	56.46		48.15		48.29		52.62		49.20		58.61		56.04		54.81		58.06		56.60
Warning / Failure	9 (15.3) /6 (10.1)	58.99		55.60		54.15		59.06		52.28		58.61		52.53		54.81		58.94		55.22
Response at 6 months			0.52		0.45		0.77		1.0		0.35		0.44		0.52		0.89		0.74		0.92
Optimal	43 (72.9)	56.46		48.15		54.15		55.10		49.38		58.61		52.53		54.81		58.94		55.46
Warning / Failure	9 (15.3) /7 (11.9)	57.73		55.60		48.29		55.35		51.29		59.81		56.04		54.81		56.30		57.09
Response at 12 months			0.65		0.85		0.49		0.92		0.29		0.43		0.91		0.37		0.64		0.40
Optimal	28 (48.3)	56.46		48.15		48.29		53.86		48.74		59.81		56.04		54.81		58.06		57.11
Warning / Failure	16 (27.6) / 14 (24.1)	56.46		55.60		54.15		56.58		52.12		58.61		52.53		54.81		58.94		55.22

P value in bold and italics are significant with P < 0.05